General 

Factors affecting Oxygen dissociation Curve

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o2 dissociation curve

 

Q. What does a right shift indicate? What are the causes of a right shift?

A right shift indicates decreased oxygen affinity. The P50 is higher for a right shifted curve.

A right shift can be caused by an increase in 4 factors:

  1. temperature
  2. [H+]
  3. pCO2
  4. red cell 2,3 DPG level.

 

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